1. Difference between cofactor, coenzyme and pathetic grp and its example??
a substance (other than the substrate) whose presence is essential for the
the activity of an enzyme.
Coenzymes are small molecules. They cannot by themselves catalyze a
reaction but they can help enzymes to do so. In technical
terms, coenzymes are organic nonprotein molecules that bind with the
protein molecule (the apoenzyme) to form the active enzyme (holoenzyme).
Prosthetic groups are cofactors that bind tightly to proteins or enzymes.
As if holding on for dear life, they are not easily removed. They can be
organic or metal ions and are often attached to proteins by a covalent
bond. The same cofactors can bind multiple different types of enzymes and
may bind some enzymes loosely, as a coenzyme, and others tightly, as a
prosthetic group.
2. What is the active site on an enzyme??
the active site is the region of an enzyme where substrate molecules bind
and undergo a chemical reaction. The active site consists of residues that
form temporary bonds with the substrate (binding site) and residues that
catalyze a reaction of that substrate (catalytic site).